Education
- PhD, Organic Chemistry, from Northeastern University – Center for Drug Discovery
- BS, Chemistry; Molecular and Cell Biology, from University of Connecticut
Courses
- CHEM 224L Organic Chemistry I Lab
- CHEM 225L Organic Chemistry II Lab
- CHEM 343 Advanced Topics in Modern Chemistry — Medicinal Chemistry
Licenses/Certifications
- Pharmacology — Harvard Medical School HMX Fundamentals, 2024
- Inclusive STEM Teaching project — National Science Foundation EdX, 2023
Publications/Presentations
Johnston, M.R.; Sobhi, H.F.; El Hajjar, A. Synthesis and Characterization of Substrates for Grafting Polymers Used in Medical Plastics. Chemical Data Collections. 2021, 31, 100621.
Johnston, M.R. Chemistry of Cannabis: An Interdisciplinary Course. J. Chem. Educ. 2020, 97, 12, 4311.
Johnston, M.R.; Sobhi, H.F. Advances in Fatty Acid Analysis for Clinical Investigation and Diagnosis using GC/MS Methodology. J Biochem Analyt Stud 2017, 3(1), 1.
Johnston, M.; Makriyannis, A.; Whitten, K.; Drew, C.; Best, F. Bio-catalyzed Regioselective Synthesis in Undergraduate Organic Laboratories: Multi-step Synthesis of 2-Arachidonoylglycerol. J. Chem. Educ. 2016, 93, 2080.
Johnston, M. Endocannabinoid Enzymes Monoacylglycerol Lipase and Diacylglycerol Lipase: Biochemical Studies and Novel Ligands. Ph.D. Dissertation, Northeastern University, Boston, MA 2012.
Johnston, M.; Bhatt, S.R.; Sikka, S.; Gatley, S.J.; Duclos, Jr., R.I. Assay and Inhibition of Diacylglycerol Lipase Activity. Bioorg. Med. Chem. Lett. 2012, 22, 4585.
Duclos, Jr., R.I.; Johnston, M.; Vadivel, S.K.; Makriyannis, A.; Glaser, S.T.; Gatley, S.J. A Methodology for Radiolabeling of the Endocannabinoid 2-Arachidonoylglycerol (2-AG). Journal of Organic Chemistry 2011, 76, 2049.
Duclos, Jr., R.I.; Gatley, S.J.; Bhatt, S.; Johnston, M. The Preparation of 2-O-[1’-14C] arachidonoyl-1-O-stearoyl-sn-glycerol. Journal of Labeled Compounds and Radiopharmaceuticals 2009, 52, 324 – 326.
Znovok, N.; Williams, J.; Johnston, M.; Pandarinathan, L.; Karageorgos, I.; Janero, D.R.; Li, J.; Krishnan, S.C.; Makriyannis, A. Full Mass Spectrometric Characterization of Human Monoacylglycerol Lipase Generated by Large-Scale Expression and Single-Step Purification. Journal of Proteome Research 2008, 7, 2158 – 2164.
Znovok, N.; Williams, J.; Johnston, M.; Pandarinathan, L.; Karageorgos, I.; Janero, D.R.; Krishnan, S.C.; Makriyannis, A. Covalent Inhibitors of Human Monoacylglycerol Lipase: Ligand-Assisted Characterization of the Catalytic Site by Mass Spectrometry and Mutational Analysis. Chemistry and Biology 2008, 15, 854 – 862.