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Bachelor of Arts
Master of Arts
Doctor of Philosophy
As people age they often lose some of their physical and mental powers. My research investigates treatments that may prevent or reverse deficits in certain types of learning and memory. Most recently, I've been studying the effects of a normal diet supplemented with fruit on brain function and learning and memory. Colorful fruits and vegetables that are high in antioxidants, like blueberries, strawberries and spinach, appear to help the old brain stay young and may slow, or even reverse, decrements in learning and memory associated with normal aging.
Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus.
Shukitt-Hale, B., Lau, F.C., Carey, A.N*., Galli, R.L., Spangler, E.L., Ingram, D.K., and Joseph, J.A.
Nutritional Neuroscience 2008, 11(4) 172-181.
Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection.
Galli, R.L., Bielinski, D.F., Szprengiel, A., Shukitt-Hale, B., and Joseph, J.A.
Neurobiology of Aging 2006, 27, 344-350.
Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress.
Shukitt-Hale, B., Galli, R.L., Meterko, V*, Carey, A*, Bielinski, D.F., McGhie, T., and Joseph, J.A.
Age. 2005, 27, 49-57.
Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory.
Andres Lacueva, C., Shukitt-Hale, B., Galli, R.L., Jauregui, O., Lamuela-Raventos, R.M., and Joseph, J.A.
Nutritional Neuroscience 2005, 8, 111-120.
Assessment of animal behavior.
Galli R.L., pp. 25-38. In Lieberman, H.R., Kanarek, R.B., and Prasad, C. (eds.)
Nutritional Neuroscience: Overview of an Emerging Field. Nutrition, Brain and Behavior Series, CRC Press, Taylor & Francis Group, LLC, Boca Raton, FL. 2005. (Book Chapter)
Fruit polyphenolics and brain aging: Nutritional interventions targeting age-related neuronal and behavioral deficits.
Galli, R.L., Shukitt-Hale, B., Youdim, K.A., and Joseph, J.A. In: Harman, D. ed.
Increasing the Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process,
Annals of the New York Academy of Science 2002, 959, 128 132.
Antisense oligonucleotide sequences targeting the muscarinic type 2 acetylcholine receptor enhance performance in the Morris water maze.
Galli, R.L., Fine, R.E., Thorpe, B.C., Shukitt-Hale, B., and Lieberman, H.R.
International Journal of Neuroscience 2000, 103:53-68.
*Denotes Simmons undergraduate authors
Beta amyloid, ROS, and the regulation of transmitter release. Bolla, M, Lifvergren, A*, Pinkham, J*, Schmidt, C*, Browne, S*, Galli, RL, and Gray, DB. Society for Neuroscience 41st Annual Meeting, Washington, DC, November, 2011
Role of polyphenols on cognitive function in adult and elderly. R.L. Galli
Symposium on Nutrition and Cognition: Towards Research and Application for Different Life Stages, Kuala Lumpur, Malaysia, October, 2010.
Educating women in the neurosciences: An undergraduate animal behavior laboratory course.
R.L.Galli. Society for Neuroscience 37th Annual Meeting, San Diego, CA, October, 2007
Educating Women in the Neurosciences: Integrating Information Literacy and Laboratory Activities. R.L. Galli & J.M. Duvernay. Society for Neuroscience Annual Meeting, November, 2003.
Correlating Brain/Behavior Relationships in Aging: the Effects of Diets High in Berry Fruit Polyphenolics. Galli, RL, Shukitt-Hale, B, Bielinski, D, Carey, A* & Joseph, J. American Aging Association Annual Meeting, June, 2003.
The Effects of Antioxidants on Cognitive and Motor Functioning in Aging 344 Fischer Rats. Birak, N*, Carlson, H*, Harrison, M*, Hughes, R*, Meterko, V* & Galli, RL.
North East Under/graduate Research Organization for Neuroscience Annual Conference, Wheaton College, May 2003.
Dietary Antioxidants and Neuronal Aging. R.L. Galli, featured speaker
Throne Holst Symposium in Nutrition, Oslo, Norway, November, 2002.