Simmons is governed by a 40-member Board of Trustees from 14 states and one other country:
- Carmen A. Baez '79, '03 HD
- Lauren J. Brisky '73
- Deborah C. Brittain '74SW
- Jane Buyers-Russo '81
- Christian Pope Campbell '91
- Jennifer Kelly Choi '87
- Barbara Latz Cohen '68
- Dwight Crane
- Helen G. Drinan '75LS, '78SM
- Atsuko T. Fish
- James D. Flynn P '12, P '14
- Jill Greenthal '78
- Karen Hammond
- Anne C. Hodsdon '75, '77GS
- John W. Humphrey
- Yvonne Jackson
- Stephen P. Jonas
- Leslie Lake
- Kathleen Morrissey LaPoint '84
- Dr. Ngina Lythcott '67
- Judith Samdperil Mann '83
- Stephen P. McCandless
- Jacqueline C. Morby '78SM
- Susan Ollila '66
- Denise Doherty Pappas '71, '85SM
- Regina Pisa
- Carol Waller Pope '74
- Emily Scott Pottruck '78
- Faith M. Richardson '84
- Jo-Ann Robotti '75
- Katie I. Schuller-Bleakie
- Carole Seigel '80SM
- Toby M. Sloane '60
- Paula A. Sneed '69
- Winston Tabb '72LS
- Janet I. Tobin, '67
- Pam J. Toulopoulos '73
- Andrea Waldstein '60SW
- Roslyn Watson '71
- Amy E. White '81
