Since 1973, the School has pursued a unique mission of educating women to be exceptional leaders. Beginning in  2015, the School of Business began admitting men to the MBA program which rigorously educates students for success in management while also helping them acquire the knowledge, experience and confidence needed to express a more contemporary and collaborative form of workplace leadership.  The MBA in Healthcare provides a uniquely designed program with over 60% of the courses specific to the healthcare industry.

The School gives women and men the tools to lead successfully in Fortune 500 corporations, healthcare organizations, entrepreneurial ventures, government agencies or nonprofit organizations, while also enabling them to work constructively for economic and social purpose. Simmons prepares its students to lead and manage effectively and ethically in a world that demands no less.

The School of Business is committed to providing premier business education to MBA, MBA in Health Care, and its undergraduate students. The Simmons School of Business is accredited by AACSB International, the Association to Advance Collegiate Schools of Business. Founded in 1916, AACSB encourages peer review and continuous improvement. Only 32% of business schools in the U.S. and less than 5% worldwide have earned and retained this distinguished hallmark of excellence in management education.

Simmons College is accredited by the New England Association of Schools and Colleges, the nation's oldest regional accrediting body. Established in 1885, NEASC serves 1,800 schools, colleges and universities. Simmons has also received considerable external recognition, having been named in the Princeton Review "Best 361 Colleges," an honor held by only 15% of the four-year undergraduate colleges in America and "Best College" (Master's Level University, Northern US), U.S. News & World Report.